Staff Optical Engineer

Location: San Jose, CA
Req ID: 22-CG-007


Job Title:  Staff Optical Engineer

Reports To: VP of Engineering

Department: Advanced Research Center

Location: San Jose, CA


Job Summary

As one of the key team members, this position will play the key role of creating groundbreaking concepts  in advanced sequencing technology and next generation technologies for multi-omics tools. You will work closely with talented multidisciplinary team, including Hardware, Software, Image Analysis, Camera Imaging, & Firmware. You will be responsible for identifying future technology within your area and collaborate with Global teams of scientists and engineers to complete proof of concept as well as transferring proven technology to product development.


Major Duties and Responsibilities

  • Serve as a key expert in Optics and Image Analysis technologies to contribute to definition of product technology directions and roadmaps.
  • Partner with technical leads in biochemistry, flow cell technology, algorithms and system hardware to invent and develop optical systems architecture to underpin future sequencing and multi-omics products.
  • Plan, develop, model, and analyze optical and system designs. Create, test and optimize various prototypes from elements and subsystems to complex integrated systems in the lab environment.
  • Extensively collaborate with overseas Engineering team to further develop system concepts and successfully transfer to Product Development team.
  • Contribute to data-driven decision making by crafting multifactorial experiments, collect and analyze data, presenting and discussing results.
  • Contribute to long term planning activities and develop budgets for capital expenditures, external services and labor.
  • Perform other work related duties as assigned.


Minimum Qualifications

  • 5+ years experience in optical system integration and design for instrumentation.
  • Experience in an R&D environment focused on instrument design. Experience in the use of imaging optics, filters, mirrors, photodiode, CCD/CMOS, lasers and other light sources. Hands-on experience in image processing, microscopy or fluorescence detection system design and detector technologies.
  • Strong hands-on experience with optical systems in a lab and manufacturing environment required.
  • Knowledge of optical modeling, data acquisition and analysis, and system modeling using tools such as Zemax, ImageJ, JMP, MATLAB, Python, Excel, LabVIEW, etc.
  • Strong problem-solving skills and the ability to respond quickly to changes in project requirements
  • Demonstrated ability working in a global matrixed environment.
  • Excellent organizational and communication skills, including the ability to efficiently evaluate, prioritize, and handle multiple projects and priorities.
  • Excellent written and oral communication skills.


Other requirements

  • Travel at 5-10% level.



  • MS/PhD in an Engineering, Optical Engineering, Applied Physics, or related field.


Preferred Qualifications

  • Experience with life science hardware systems, including fluidics, mechanical, and pneumatic subsystems, troubleshooting and optimization of system level performance desired.
  • Image processing and Algorithms development experience, ideally base calling algorithms.
  • Camera systems and Immersion optics development experience.


The base salary range for this position is $107,000 to $135,000 . This position will also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. The actual compensation paid to any individual for this position may vary depending on factors such as experience, internal equity, market conditions, education/training, and skill level. Actual compensation will be confirmed in writing at the time of offer.



Complete Genomics offers its eligible employees and their dependents (including domestic partners) a comprehensive and competitive benefits package. Complete Genomics contributes to the benefits package.

  • Medical, Dental and Vision Coverage
  • Life and AD&D Insurance
  • Long-term and Short-term Disability Insurance
  • Voluntary Life and AD&D Insurance
  • Health Savings Account (HSA)
  • Flexible Spending Accounts (FSA)
  • Domestic Partner Benefits
  • Commuter Program
  • Employee Assistance Program
  • 401(k) Retirement Plan
  • 20 PTO days and 11 holidays per year


About Us

Complete Genomics is a leading producer of advanced genomic sequencing technologies, and its multi-omics platforms include genetic sequencing, mass spectrometry, and laboratory automation based in San Jose, California. Using our proprietary sequencing instruments, chemistry, and software, Complete Genomics is committed to building core tools and technology to lead life science through intelligent innovation.

Complete Genomics focuses on R&D, production and sales of DNA sequencing instruments, reagents and related products to support life science research, agriculture, precession medicine and healthcare. With thousands of instruments worldwide, our proven technologies and products are well accepted by the scientific research community and clinical diagnostic customers.

We are currently one of the fastest growing biotechnology companies in the United States with 100+ employees spanning multiple scientific, engineering and technical specialties working in R&D, production and sales of DNA sequencing instruments, advanced robotic sample preparation, reagents, and related products to support life science research, agriculture, precision medicine and healthcare.


Complete Genomics does not accept unsolicited agency resumes.  Please do not forward unsolicited agency resume to our website, employees or Human Resources. 

Complete Genomics will not pay fees to any third-party agency or firm and will not be responsible for any agency fees associated with unsolicited resumes. Unsolicited resumes received will be considered property of Complete Genomics and will be processed accordingly without fee.

Complete Genomics has the sole discretion to determine with whom we will enter into a contract.


Complete Genomics provides equal employment opportunity without regard to race, color, religion, sex, national origin, sexual orientation, gender identity and/or expression, age, disability, veteran or uniformed service status, or any other characteristic protected by applicable law.

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